Syngenta receives federal registration for Trefinti® nematicide/fungicide

Trefinti is powered by a new active ingredient for advanced turfgrass protection against nematodes and soilborne diseases.

Syngenta announced today that the Environmental Protection Agency (EPA) has granted federal registration under Section 3 of the Federal Insecticide, Fungicide and Rodenticide Act (FIFRA) for Trefinti® nematicide/fungicide. State registrations are actively being pursued and are anticipated to be available soon. Powered by TYMIRIUM® technology, this new solution for turfgrass managers selectively reduces nematode populations and controls soilborne diseases on greens, tees and fairways to help achieve robust root growth. Trefinti controls key plant-parasitic nematode species, including sting, lance, root-knot and Anguina. It is also the only nematicide labeled to control fungal diseases, including spring dead spot, take-all root rot and mini ring.

“While light sandy soils have historically been conducive to nematode issues, nematodes can be found in all soil types,” said Lane Tredway, Ph.D., technical services manager for turf at Syngenta. “Over the past decade, we have conducted extensive testing to address this growing issue for turfgrass managers. The sustained R&D investment has led to Trefinti, a groundbreaking solution for controlling elusive, damaging nematodes that also offers powerful control of root diseases.”

Comparison photos showing the impact of Trefinti in controlling rooting damage caused by lance nematodes
Source: The Dormie Club, West End, North Carolina. ‘Penn A-1/A-4’ creeping bentgrass putting greens. Treatments applied June 5, July 3, Sept. 23 and Oct. 21, 2024, and April 3 and April 30, 2025. Watered-in immediately with 1/8” of irrigation. Photos taken June 24, 2025.

To enhance nematode control and reduce the risk of resistance, Syngenta recommends rotating Trefinti and Divanem® nematicide, particularly in areas with high nematode populations or substantial damage. A rotation with Divanem provides broader-spectrum control of key nematode species, including spiral and stubby root, as well as resistance management for sting and root-knot species. Trefinti can be applied as a broadcast spray or spot treatment.

“Trefinti delivers what superintendents have been asking for—broader-spectrum nematode control including lance, plus the added benefit of soilborne disease protection in one solution,” said Stephanie Schwenke, turf market manager at Syngenta.

Spring Dead Spot Control in “TifEagle” Bermudagrass

Comparison photos showing the impact of Trefinti in controlling spring dead spot in Bermudagrass, compared to Resilia fungicide
Source: Joseph Roberts, Ph.D., Clemson University
Treatments applied July 2, July 30, Aug. 27 and Sept. 24, 2024. Watered-in immediately with 1/8” of irrigation. Photos taken May 15, 2025.

For more information and to view trial data, visit GreenCastOnline.com/Trefinti or contact your local Syngenta territory manager. Join the conversation online — connect with us @SyngentaTurf on X and with #Time4Trefinti.

For more information about Syngenta, visit GreenCastOnline.com. Join the conversation online ― connect with us on LinkedIn.

Media Contacts
Mark LaFleur
336-632-6138
mark.lafleur@syngenta.com

Lindsay Rusczak
919-896-2750
lrusczak@gscommunications.com

Web Resources
GreenCastOnline.com/Trefinti
@SyngentaTurf

About Syngenta
Syngenta continues to be a global leader in agricultural innovation with a presence in more than 100 countries. Syngenta Professional Solutions is focused on developing tomorrow’s technologies and practices that empower customers today to protect and enhance the places where people live, work and play, all while preserving our planet. Its bold scientific discoveries deliver better benefits for customers and society on a bigger scale than ever before. Guided by its Sustainability Priorities, Syngenta is developing new technologies and investing in digital solutions that help customers maintain beautiful landscapes and keep public spaces healthy. Syngenta Crop Protection is headquartered in Basel, Switzerland; Syngenta Seeds is headquartered in the United States. Follow us on, YouTube & X.

Cautionary Statement Regarding Forward-Looking Statements
This document may contain forward-looking statements, which can be identified by terminology such as ‘expect’, ‘would’, ‘will’, ‘potential’, ‘plans’, ‘prospects’, ‘estimated’, ‘aiming’, ‘on track’ and similar expressions. Such statements may be subject to risks and uncertainties that could cause the actual results to differ materially from these statements. For Syngenta, such risks and uncertainties include risks relating to legal proceedings, regulatory approvals, new product development, increasing competition, customer credit risk, general economic and market conditions, compliance and remediation, intellectual property rights, implementation of organizational changes, impairment of intangible assets, consumer perceptions of genetically modified crops and organisms or crop protection chemicals, climatic variations, fluctuations in exchange rates and/or commodity prices, single source supply arrangements, political uncertainty, natural disasters, and breaches of data security or other disruptions of information technology. Syngenta assumes no obligation to update forward-looking statements to reflect actual results, changed assumptions or other factors.

© 2025 Syngenta. 410 Swing Road, Greensboro, NC, 27409. Important: Always read and follow label instructions. Some products may not be registered for sale or use in all states or counties and/or may have state-specific use requirements. Please check with your local extension service to ensure registration and proper use. Divanem is a Restricted Use Pesticide. Divanem®, GreenCast®, Trefinti®, TYMIRIUM® and the Syngenta logo are trademarks of a Syngenta Group Company. All other trademarks are the property of their respective third-party owners.

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